Dolores Costello (Drew Barrymore's grandmother); see her in, among other movies, The Magnificent Ambersons, 1942, directed by Orson Welles (made a number of years after this photo, of course). An excellent movie.
Ethel Barrymore c. 1901~She was one of the twentieth century’s most elegant, beautiful and gifted actresses. She was the sister of actors John Barrymore and Lionel Barrymore, the aunt of actor John Drew Barrymore, and the great-aunt of actress Drew Barrymore.
Drew in the role of Petruchio. John Drew, Jr. (November 13, 1853–July 9, 1927) was an American stage actor noted for his roles in Shakespearean comedy, society drama, and light comedies. He was the eldest son of John Drew, who had given up a blossoming career in whaling for acting, and Louisa Lane Drew, and the brother of Louisa Drew, Georgiana Drew & Sidney Drew.