Sucralose, A Synthetic Organochlorine Sweetener: Overview Of Biological IssuesThis review of the scientific literature on sucralose (Splenda) is cause for concern. Some of the biological effects of sucralose include:~ alterations in insulin, blood glucose, and glucagon-like peptide 1 (GLP-1) levels,~ metabolism of sucralose in the gastrointestinal tract to metabolites whose identity and safety profile are unknown,~ induction of cyctochrome P450 and P-glycoprotein in the gastrointestinal ...

Sucralose, A Synthetic Organochlorine Sweetener: Overview Of Biological Issues. Journal of Toxicology and Environmental Health, Part B: Vol.

Multidrug ABC transporter, P-glycoprotein (with sound)

Multidrug ABC transporter, P-glycoprotein (with sound)

#Health Herpes Simplex Virus I II Glycoprotein B (HSV III Herpes Simplex Virus 1 HSV1 Herpes Simplex Virus 2 HSV2) H2033-21-100ug

NT Cyclin-dependent kinase Cell division protein kinase Mediator complex subunit Mediator of RNA polymerase II transcription subunit Protein kinase (Azide free) (HRP),

Inhibition of p-glycoprotein by quinidine increasing concentration of digoxin

How quinidine increases the concentration of digoxin when given concomitantly?

Antibodies and their antigen. Computer model showing the molecular structure of two anti-P-glycoprotein antibodies (upper left and right) and the P-glycoprotein (blue) to which they respond. These antibodies will bind to the glycoprotein, preventing it from functioning.  ©Laguna Design/Science Source

SP8395: Antibodies and their antigen

Antibodies and their antigen

The condition of upset stomach can be described in many ways. It could be…

Upset Stomach Causes

What are Colon Spasms? Colon spasms, likewise described as Irritable Bowel Syndrome (IBS), hurt contractions of the muscle of the lower digestive system.

P-Glycoprotein

P-Glycoprotein

PowerPoint ® Lecture Slides prepared by Janice Meeking, Mount Royal College C H A P T E R Copyright © 2010 Pearson Education, Inc. 16 The Endocrine System:

PowerPoint ® Lecture Slides prepared by Janice Meeking, Mount Royal College C H A P T E R Copyright © 2010 Pearson Education, Inc. 10 The Muscular System:

Splenda alters gut microflora and increases intestinal p-glycoprotein and…

Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome in male rats.

Figure 3: Unhealthy diets such as high fat diets downregulate hepatic drug metabolism with the corruption of insulin therapy in diabetes and aging. Amyloid beta metabolism in the brain and liver are connected to drug metabolism and defective hepatic drug metabolism may be the primary defect in Type 3 diabetes with acceleration of neuronal apoptosis by abnormal brain amyloid beta metabolism associated with Type 1 or Type 2 diabetes. Abbreviations: P-gp1, P glycoprotein, PXR, pregnane X…

Diet and Nutrition Reverse Type 3 Diabetes and Accelerated Aging Linked to Global Chronic Diseases

Herbal elixir anyone?  Mol Neurobiol. 2016 Dec 9. [Epub ahead of print] Matrine Treatment Blocks NogoA-Induced Neural Inhibitory Signaling Pathway in Ongoing Experimental Autoimmune Encephalomyelitis.  Kan QC Zhang HJ Zhang Y Li X Xu YM Thome R Zhang ML Liu N Chu YJ Zhang GX Zhu L. Abstract Myelin-associated inhibitors such as NogoA myelin-associated glycoprotein (MAG) and oligodendrocyte myelin glycoprotein (OMgp) play a pivotal role in the lack of neuroregeneration in multiple sclerosis an…

Nina Koduru identifies 5 fatal foods that endanger your life and offers a solution: an untested remedy with unsubstantiated claims.

ABC Transporter Pgp-1 ( P-glycoprotein-1) - YouTube

We want to outline how this membrane transporter found in nearly every human cell is involved in human cancer multi-drug resistance.

New Diet Pepsi Now Aspartame Free And Replaced With This Deadly Sweetener

New Diet Pepsi Now Aspartame Free And Replaced With This Deadly Sweetener

How Splenda makes you fat. Splenda reduces the amount of good bacteria in the intestines by 50%, increases the pH level in the intestines, contributes to increases in body weight and affects the P-glycoprotein (P-gp) in the body in such a way that crucial health-related drugs could be rejected"  How much Splenda caused this? It was the equivalent of 7 packets. Over time and daily use this could have extreme consequences’ on ones health and weight.

Do you put Splenda in your coffee? Or use it in your baked goods, instead of regular sugar or other natural alternatives? You may think you are making a better choice, but in fact, you are doing more harm than good. Many foods labeled as "healthier f

Thou shall have a fishy on a little dishy thou shall have a fishy when the 3Rs boats come in    Kulkarni P Yellanki S Medishetti R Sriram D Saxena U Yogeeswari P. Novel Zebrafish EAE model: A quick in vivo screen for multiple sclerosis. Mult Scler Relat Disord. 2017 Jan;11:32-39. doi: 10.1016/j.msard.2016.11.010.  INTRODUCTION:  METHODS:  RESULTS:  DISCUSSION:  Highlights  Zebrafish develop EAE  Zebrafish EAE is treated with MS DMT  You don't need to use mice or larger animals to look for…

Zebrafish: a versatile in vivo model for drug safety assessment.

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