Potassium channel

The bacterial potassium channel is a transmembrane protein. This video explains the structure and functions of potassium channel.

ndeed, potassium channel–modulating agents have demonstrated antitumor efficacy. Potassium channels regulate cancer cell behaviors such as proliferation and migration through both canonical ion permeation–dependent and noncanonical ion permeation–independent functions. Given their cell surface localization and well-known pharmacology, pharmacological strategies to target potassium channel could prove to be promising cancer therapeutics.

Targeting potassium channels in cancer

Thunder God Vine: Celastrol modulates expression of pro-inflammatory cytokines, MHC II, HO-1, iNOS, NF-κB, Notch-1, AKT/mTOR, CXCR4, TRAIL receptors DR4 and  DR5, CHOP, JNK, VEGF, adhesion molecules, proteasome activity, topoisomerase II, potassium channels, and heat  shock response.

Thunder God Vine: Celastrol modulates expression of pro-inflammatory cytokines, MHC II, HO-1, iNOS, NF-κB, Notch-1, AKT/mTOR, CXCR4, TRAIL receptors DR4 and DR5, CHOP, JNK, VEGF, adhesion molecules, proteasome activity, topoisomerase II, potassium channels, and heat shock response.

Graph showing ventricular action potential with delayed repolarization by potassium channel blockade. K-channel blockers comprise the Class III antiarrhythmic compounds according to the Vaughan-Williams classification scheme. These drugs bind to and block the Kchannels that are responsible for phase 3 repolarization. Therefore, blocking these channels slows (delays) repolarization, which leads to an increase in action potential duration and an increase in the effective refractory period…

Potassium-Channel Blockers (Class III Antiarrhythmics): Graph showing ventricular action potential with delayed repolarization by potassium channel blockade

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Do you have fitness questions? Are you struggling to know how to achieve your fitness goals? Is your mind confused by all the information regarding fitness and not sure what to believe? Well never fear GenFit/Bodysharp is here to help. If you got questions we have the answers! Today's question "Are nuts good for you? Nuts are rich in heart-healthy polyunsaturated fats and monounsaturated fats which lower LDL or "bad" cholesterol; plus they are a good source of phytosterols compounds that…

Wikipedia.org/***CELLS-- Potassium Channels-- are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium-selective pores that span cell membranes. Furthermore potassium channels are found in most cell types and control a wide variety of cell functions

This image shows a top view of potassium ions (purple) moving through potassium channel.

Changing the (potassium) channel? - Nature.com

Changing the (potassium) channel? - Nature.com

Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation

Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation

Education: Big Conductance Potassium Channels.   So today we continue on the potassium channel journey and today we do the calcium activated potassium channels There are small conductance intermediate and big conductance calcium activated potssium channels called the SK channels and theBKchannels.  They are so called because of their small single channel conductance in the order of 10 pS(picoseimens = unit of electrical conductance The SK channel family contains 4 members -SK1SK2SK3 andSK4…

Education: Big Conductance Potassium Channels. So today we continue on the potassium channel journey and today we do the calcium activated potassium channels There are small conductance intermediate and big conductance calcium activated potssium channels called the SK channels and theBKchannels. They are so called because of their small single channel conductance in the order of 10 pS(picoseimens = unit of electrical conductance The SK channel family contains 4 members -SK1SK2SK3 andSK4…

Mouse Anti-Kv3.1 Potassium Channel Antibody [S16B-8] used in Western Blot (WB) on Rat brain lysates (SMC-313)

Mouse Potassium Channel Antibody used in Western Blot (WB) on Rat brain lysates

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