A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural domains. One domain may appear in a variety of different proteins.

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural domains. One domain may appear in a variety of different proteins.

CDD The Conserved Domain Database is a resource for the annotation of functional units in proteins. Its collection of domain models includes a set curated by NCBI, which utilizes 3D structure to provide insights into sequence/structure/function relationships.

CDD The Conserved Domain Database is a resource for the annotation of functional units in proteins. Its collection of domain models includes a set curated by NCBI, which utilizes 3D structure to provide insights into sequence/structure/function relationships.

by Tom Bunzel, Collective-Evolution Have you thought deeply about the latest discovery in genetics? DUF1220 – “DUF” stands for a (protein) domain of unknown function –presumably “junk DNA.” …

by Tom Bunzel, Collective-Evolution Have you thought deeply about the latest discovery in genetics? – “DUF” stands for a (protein) domain of unknown function –presumably “junk DNA.

Figure 1 from Insights into Protein Sequence and Structure-Derived Features Mediating 3D Domain Swapping Mechanism using Support Vector Machine Based Approach Published in Bioinformatics and Biology Insights

Figure 1 from Insights into Protein Sequence and Structure-Derived Features Mediating Domain Swapping Mechanism using Support Vector Machine Based Approach Published in Bioinformatics and Biology Insights

PolA1, a putative DNA polymerase I, is coexpressed with PerR and contributes to peroxide stress defenses of group A Streptococcus

In Staphylococcus aureus, fur is an interactive regulator with PerR, contributes to virulence, and Is necessary for oxidative stress resistance through positive regulation of catalase and iron homeostasis

The Human Brain with people

Protein Domain Found To Be Key At Explaining Evolution Of Human Brain Size

Targeting Protein Domains with CRISPR on The Scientist

Practical Aspects of Small Molecule Drug Discovery: At the interface of biology, chemistry and pharmacology, June ‎Hinxton, UK

Lectins are an inherent component of plant immunity systems. Van Holle et al. study the occurrence and evolution of the family of Nictaba-like lectin genes and report the omnipresence of these genes in a wide range of plant species including major food crops.  Chromosomal distribution of NLL genes across different species. All chromosomes are visualized in distinct colours and chromosome zero is defined by the scaffolds that could not be mapped on any of the chromosomes. Many of these…

Evolution and structural diversification of Nictaba-like lectin genes in food crops

Lectins are an inherent component of plant immunity systems. Van Holle et al. study the occurrence and evolution of the family of Nictaba-like lectin genes

Protein of the Week: sushi Fun Fact: The intestines, ovaries and liver of fugu (or blowfish) contain a poison called tetrodotoxin, which is 1,200 times deadlier than cyanide (Time Magazine 2010). Science Fact: Sushi domain containing 2 (SUSD2) is a type I transmembrane protein that is highly expressed on breast cancer cells. #antibodies

Protein of the Week: sushi Fun Fact: The intestines, ovaries and liver of fugu (or blowfish) contain a poison called tetrodotoxin, which is 1,200 times deadlier than cyanide (Time Magazine 2010). Science Fact: Sushi domain containing 2 (SUSD2) is a type I transmembrane protein that is highly expressed on breast cancer cells. #antibodies

Pinterest
Search