Discovery helps engineer more accurate for CRISPR editing - Scientists identified master controller of DNA cutting and have tweaked it to produce a hyper-accurate gene editor with the lowest level of off-target cutting to date.
by Tom Bunzel, Collective-Evolution Have you thought deeply about the latest discovery in genetics? – “DUF” stands for a (protein) domain of unknown function –presumably “junk DNA.
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural domains. One domain may appear in a variety of different proteins.