Blood circulates throughout the human body and contains molecules drawn from virtually every tissue, including the microbes and viruses which colonize the body. Through massive shotgun sequencing of circulating cell-free DNA from the blood, we identified hundreds of new bacteria and viruses which represent previously unidentified members of the human microbiome.

Blood circulates throughout the human body and contains molecules drawn from virtually every tissue, including the microbes and viruses which colonize the body. Through massive shotgun sequencing of circulating cell-free DNA from the blood, we identified hundreds of new bacteria and viruses which represent previously unidentified members of the human microbiome.

Shotgun sequencing

What is shotgun sequencing?

Shotgun sequencing involves randomly breaking up DNA sequences into lots of small pieces and then reassembling the sequence by looking for regions of overlap.

Shotgun-Sequencing Learning | medaholic

Shotgun-Sequencing Learning | medaholic

Shotgun sequencing | HHMI BioInteractive

In shotgun sequencing many copies of the entire genome are

Craig Venter | Es un biólogo y hombre de negocios estadounidense. Fue el presidente fundador de Celera Genomics, haciéndose famoso al arrancar su propio Proyecto Genoma Humano en 1999, al margen del consorcio público, con propósitos comerciales y utilizando la técnica "shotgun sequencing".

Craig Venter | Es un biólogo y hombre de negocios estadounidense. Fue el presidente fundador de Celera Genomics, haciéndose famoso al arrancar su propio Proyecto Genoma Humano en 1999, al margen del consorcio público, con propósitos comerciales y utilizando la técnica "shotgun sequencing".

Plant natural product research can be facilitated through genome and transcriptome sequencing approaches that generate informative sequence and expression datasets that enable characterization of biochemical pathways of interest. As the overwhelming majority of plant-derived natural products are derived from species with little, if any, sequence and/or genomic resources, the ability to perform whole genome shotgun sequencing and assembly has been and will continue to be transformative as…

Plant natural product research can be facilitated through genome and transcriptome sequencing approaches that generate informative sequence and expression datasets that enable characterization of biochemical pathways of interest. As the overwhelming majority of plant-derived natural products are derived from species with little, if any, sequence and/or genomic resources, the ability to perform whole genome shotgun sequencing and assembly has been and will continue to be transformative as…

Image result for genome shotgun sequencing

Image result for genome shotgun sequencing

Learn the principles of how DNA is sequenced and assembled into whole genomes using the Sanger method, shotgun sequencing, or ultra-deep sequencing.

Using information from molecular research, this animation shows how DNA is replicated at the molecular level. It involves an enzyme that unwinds the DNA, and other enzymes that copy the two resulting strands.

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