1) Reduce p-isobutylacetophenone to an alcohol using sodium borohydride 2) Convert alcohol group to a chloride using hydrochloric acid 3) Use magnesium to convert to Grignard reagent 4) Use carbon dioxide and hydrochloric acid to create Ibuprofen
Generating borane from the reaction of iodine + sodium borohydride in THF. When the color of the iodine fades it is ready. The reaction goes as seen here: So what happens here? First, iodine is reacting with one sodium borohydride, so you get borane, sodium iodide, and hydrogen iodide. Then hydrogen iodide is reacting with another sodium borohydride, so you get another borane and another sodium iodide, plus some hydrogen.
Sodium Borohydride, also known as sodium tetrahydridoborate, is a white solid, usually encountered as a powder, widely used as a reducing agent in various industries like pharmaceuticals, pulp & paper, metal recovery, textiles, organic chemical purification and others.