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Advance improves cutting and pasting with CRISPR-Cas9 gene editing.

Advance improves cutting and pasting with CRISPR-Cas9 gene editing

Advance improves cutting and pasting with gene editing

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Atomic placement of elements counts for strong concrete   http://phys.org/news/2015-01-atomic-placement-elements-strong-concrete.html?utm_source=nwletter&utm_medium=email&utm_content=splt-item&utm_campaign=daily-nwletter

Atomic placement of elements counts for strong concrete

Congo announces 9 suspected Ebola cases, including 2 deaths

Congo announces 9 suspected Ebola cases, including 2 deaths

Ebola outbreak in Democratic Republic of Congo kills 3 people, WHO says

Early Code— New research points to key properties of transfer RNA molecules and amino acids that may have supported the origin of life on Earth.

Early Code— New research points to key properties of transfer RNA molecules and amino acids that may have supported the origin of life on Earth.

La composición genética influye en el microbioma intestinal: La afirmación “somos lo que comemos” va a tener que ser ligeramente modificada, según un reciente estudio del King’s College London y la Universidad Cornell, el cual sugiere que nuestra composición genética influye en si estamos gordos o delgados, a través de la regulación de qué tipos de microorganismos conviven en nuestro cuerpo

A breakthrough in antibiotic resistance was reported last week. Scientists had re-engineered the drug vancomycin—used against extremely resistant infections

Reverse engineering improves the performance of artificial retinas.

Working backwards to give clearer vision

Working backwards to give clearer vision – Health and Disease – Medium

HIV’s unkind cut: The activating domain of Casp8p41 (green coil) fits into a groove in Bak (white). Sainski et al. reveal how an inactive caspase fragment spawned by HIV infection can still kill T cells.

HIV’s unkind cut: The activating domain of (green coil) fits into a groove in Bak (white). Sainski et al. reveal how an inactive caspase fragment spawned by HIV infection can still kill T cells.

Persuading proteins to form porous polyhedra | Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA. The custom-built protein structures might be used for drug delivery, or as reaction or crystallisation vessels.Chemistry World

Persuading proteins to form porous polyhedra

POWERING THROUGH  Inspired by the bacterium Helicobacter pylori, researchers designed microscopic, protein-coated propellers (illustrated) that can push through thick mucus.   ~~ Alejandro Posada

To push through goo, use itty, bitty propellers

POWERING THROUGH Inspired by the bacterium Helicobacter pylori, researchers designed microscopic, protein-coated propellers (illustrated) that can push through thick mucus.

Sticky-flares label endogenous RNA with quantifiable fluorescent ‘flares,’ allowing for RNA tracking in live cells. Credit: Chad. A. Mirkin, William E. Briley

Sticky-flares label endogenous RNA with quantifiable fluorescent ‘flares,’ allowing for RNA tracking in live cells. Mirkin, William E.

Hemotin, a novel conserved regulator of phagocytosis

PLOS Biology on

Hemotin, a small ORF-encoded transmembrane peptide, regulates endosomal maturation and phagocytosis in fruit fly macrophages through the adaptor protein and phosphatidylinositol Hemotin's structure and function are conserved from flies to vertebrates.

Phospholipase A2 (PLA2) in bee venom is introduced into human skin and cleaves ubiquitous phospholipids into free fatty acids and lysophospholipids that function as neoantigens. These fatty acid neoantigens are now available for sampling by epidermal Langerhans cells, which load them onto CD1a proteins and present them at their surface to skin-resident CD1a-reactive T cells. These T cells produce cytokines such as IL-22 that contribute to the inflammatory response

Bee venom stirs up buzz in antigen presentation

Moonlighting molecules: Finding new uses for old enzymes

A collaboration between the University of Cambridge and MedImmune, the global biologics research and development arm of AstraZeneca, has led researchers to identify a potentially significant new application for a well-known .

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