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Antioxidant defence systems have received increasing attention in the pathophysiology of psychiatric disorders, including: bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ). Recently, we reported decreased glutathione (GSH) levels in post-mortem prefrontal cortex from patients with BD, MDD, and SCZ. To explore this further, we evaluated the levels of two glutathione S-transferase (GST) isoforms via immunoblotting: GST Pi and GST Mu. GST Pi levels were not…

Prefrontal cortex glutathione S -transferase levels in patients with bipolar disorder, major depression and schizophrenia | International Journal of Neuropsychopharmacology | Oxford Academic

Antioxidant defence systems have received increasing attention in the pathophysiology of psychiatric disorders, including: bipolar disorder (BD), maj

Glutathione: a novel treatment target in psychiatry - ScienceDirect

Vestibular insights into cognition and psychiatry - ScienceDirect

Diagnosis & Treatment of Bipolar Disorder | Psych Central Professional

Diagnosis & Treatment of Bipolar Disorder

Baldassano, it's great for generalist psychiatrists to talk to an expert in bipolar disorder because, let's face it, it can be a tough and confusing

When the drugs don’t work: the potential of glutamatergic antipsychotics in schizophrenia

When the drugs don’t work: the potential of glutamatergic antipsychotics in schizophrenia

N-acetylcysteine for major depressive episodes in bipolar disorder

N-acetylcysteine for major depressive episodes in bipolar disorder

N-Acetyl Cysteine as a Glutathione Precursor for Schizophrenia—A Double-Blind, Randomized, Placebo-Controlled Trial - ScienceDirect

N-Acetyl Cysteine as a Glutathione Precursor for Schizophrenia—A Double-Blind, Randomized, Placebo-Controlled Trial - ScienceDirect

Placebo-controlled augmentation trials of the antioxidant NAC in schizophrenia: A review.  - PubMed - NCBI

Placebo-controlled augmentation trials of the antioxidant NAC in schizophrenia: A review. - PubMed - NCBI

Taking the fuel out of the fire: evidence for the use of anti-inflammatory agents in the treatment of bipolar disorders.  - PubMed - NCBI

Taking the fuel out of the fire: evidence for the use of anti-inflammatory agents in the treatment of bipolar disorders.

Effects of N-acetyl cysteine on cognitive function in bipolar disorder - Dean - 2012 - Psychiatry and Clinical Neurosciences - Wiley Online Library

Bipolar disorder is characterized by progressive changes in cognition with declines in executive functioning, memory and sustained attention. Current pharmacotherapies for bipolar disorder target mood.

Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric disorders, including anxiety, psychosis, and depression. The mechanisms responsible for these effects, however, are still poorly understood. Similar to clinical ...

Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric disorders, including anxiety, psychosis, and depression. The mechanisms responsible for these effects, however, are still poorly understood. Similar to clinical ...

Integrative Treatment of Bipolar Disorder: A Review of the Evidence and Recommendations: Page 3 of 4 | Psychiatric Times

Integrative Treatment of Bipolar Disorder: A Review of the Evidence and Recommendations: Page 3 of 4 | Psychiatric Times

9 Natural Therapies for Bipolar Depression | Everyday Health

9 Natural Therapies for Bipolar Depression

Complementary therapies may help people with bipolar disorder when added to a regular schedule of prescribed medications.

Novel Treatment Avenues for Bipolar Depression | Psychiatric Times

The evidence-based approach to bipolar depression symptoms includes treatment with lithium, conventional unimodal antidepressants, lamotrigine, or divalproex.

N-Acetyl Cysteine for Depressive Symptoms in Bipolar Disorder—A Double-Blind Randomized Placebo-Controlled Trial - ScienceDirect

N-Acetyl Cysteine for Depressive Symptoms in Bipolar Disorder—A Double-Blind Randomized Placebo-Controlled Trial - ScienceDirect

There is an expanding field of research investigating the benefits of alternatives to current pharmacological therapies in psychiatry. N-acetylcysteine (NAC) is emerging as a useful agent in the treatment of psychiatric disorders. Like many therapies, ...

There is an expanding field of research investigating the benefits of alternatives to current pharmacological therapies in psychiatry. N-acetylcysteine (NAC) is emerging as a useful agent in the treatment of psychiatric disorders. Like many therapies, ...

Antioxidants May Be Deficient in Patients with Bipolar Disorder, NAC May Help : Bipolar Network News

Antioxidants May Be Deficient in Patients with Bipolar Disorder, NAC May Help : Bipolar Network News

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