his Venn Diagram does a nice job showing the affects of (or consequences for lack of) these brain chemicals. It is a nice addition to see clarity and relaxation, which are terms students can understand better than more clinical definitions
SNRI-Action block the absorption (reuptake) of serotonin & norepinephrine. They change the balance of sometimes called dual-action antidepressants. Venlafaxine (Effexor): Most popular and first SNRI. Lower selectivity than other SNRIs which may lead to more side effects. Duloxetine treats fibromyalgia, anxiety disorders & severe depression. Milnacipran treats both depression and fibromyalgia.
Endocrine Disruptors interfere with hormones and specific brain chemicals necessary for maintaining mood balance. The rising incidence of Bipolar Disorder has kept pace with the rise of toxins and chemicals dumped into our environment and food chain.